A concise procedure for the preparation of enantiopure 3-alkylpiperidines

DOI: 10.1016/S0957-4166(97)00204-8

Source and publish data:

Tetrahedron Asymmetry p. 2237 - 2240 (1997)

Update date:2022-08-17

Topics:

Authors:

Amat, Mercedes

Llor, Nuria

Hidalgo, Jose

Bosch, Joan

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0957-4166(97)00204-8

Reaction of (R)-phenylglycinol with racemic methyl 4-formylhexanoate takes place with a remarkable stereoselectivity to give two diastereomeric 6-ethyloxazolopiperidones (9:1 ratio) in 76% overall yield. After LiAlH₄ reduction and catalytic hyd

Full text of DOI:10.1016/S0957-4166(97)00204-8

Products guided by the article

Product name:(3R,8S,8aR)-8-ethyl-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine

Cas No:194149-76-3

R&D Labs maybe for 194149-76-3

Suzhou Sinosun Imp.&Exp. Corporation

website:http://www.szsinosun.com

Contact:+86-512-63488895,63488616

Address:No.758 East Jiangling Road Wujiang Economic & Technological Developmenty Zone Jiangsu China
Xian Lyphar Biotech Co., Ltd.

Contact:0086-29-89196322

Address:North of the Fifth Keji Road, Hi-Tech Industrial Zone, Xi'an City, Shaanxi Province, China
Tianjin Ji Ping Jia Chemical Co., Ltd.

Contact:18622448868

Address:tianjin
JIN TAN CHENG'EN CHEMICAL CO.,LTD.

Contact:86-519-82116250

Address:NO.102，village Dongfang，conomic development zone
TIANJIN ZHONGXIN CHEMTECH CO.,LTD.

Contact:86-022-89880739

Address:10B, Pan China International Center, No. 931 YingKou Road, TangGu, Tianjin, China, 300451

Relevant to this article

Doi:10.1021/ja01664a021
(1923)
A new method for the synthesis of N²-alkylguanosines using mitsunobu reaction as a key step

Doi:10.1081/NCN-100105245
(2001)
Self-assembly of M₂₄L₄₈ polyhedra based on empirical prediction

Doi:10.1002/anie.201108731
(2012)
Five-Step Enantioselective Synthesis of Islatravir via Asymmetric Ketone Alkynylation and an Ozonolysis Cascade

Doi:10.1002/chem.202003091
(2020)
An investigation of the equilibrium of the reaction {l-aspartate(aq) + 2-oxoglutarate(aq) = oxaloacetate(aq) + l-glutamate(aq)}

Doi:10.1006/jcht.1998.0404
(1998)
Non-peptide ITAM mimics as ZAP-70 antagonists

Doi:10.1016/S0960-894X(97)10102-0
(1997)

Article Doi