A concise procedure for the preparation of enantiopure 3-alkylpiperidines

DOI: 10.1016/S0957-4166(97)00204-8

Source and publish data:

Tetrahedron Asymmetry p. 2237 - 2240 (1997)

Update date:2022-08-17

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Authors:

Amat, Mercedes

Llor, Nuria

Hidalgo, Jose

Bosch, Joan

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Article abstract of DOI:10.1016/S0957-4166(97)00204-8

Reaction of (R)-phenylglycinol with racemic methyl 4-formylhexanoate takes place with a remarkable stereoselectivity to give two diastereomeric 6-ethyloxazolopiperidones (9:1 ratio) in 76% overall yield. After LiAlH₄ reduction and catalytic hyd

Full text of DOI:10.1016/S0957-4166(97)00204-8

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Product name:(3R,8S,8aR)-8-ethyl-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine

Cas No:194149-76-3

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