Journal of the Chemical Society. Perkin transactions II p. 39 - 42 (1982)
Update date:2022-08-10
Topics:
Maskill, H.
Wilson, Alan A.
Stereochemically pure samples of exo-bicyclo<3.2.1>octan-2-ol are obtained from hydrolysis followed by hydrogenation-hydrogenolysis of exo-3,4-dihalogenobicyclo<3.2.1>oct-2-enes.Attempted tosylation of the intermediate hydroxy-halides in these reactions by the Tipson procedure gave only exo-4-chloro-3-halogenobicyclo<3.2.1>oct-2-enes.No inversion of configuration was detected in the reactions of exo-3,4-dihalogenobicyclo<3.2.1>oct-2-enes with sodium halides in aprotic dipolar solvents.These results lead to the conclusion that the SN2' reaction in this system occurs upon covalent substrates with retention of relative configuration but inversion of absolute configuration.
View Morewebsite:http://www.enbridgepharm.com
Contact:+86-510-83591909
Address:Huishan Zone, Wuxi City, Jiangsu Province, P.R.China
Nanjing Chemlin Chemical Co., Ltd.
website:http://www.echemlin.cn
Contact:+86-25-83697070
Address:Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China
Contact:+1 (647) 918 5848
Address:2343 BRIMLEY RD., Suite 250
Mollt Biochem Co., Ltd(expird)
Contact:+86-21-38682181
Address:shanghai ,china
Huzhou City Linghu Xinwang Chemical Co.,Ltd.
Contact:86-572-3948695/3945236
Address:huzhou
Doi:10.1246/cl.2006.1402
(2006)Doi:10.1039/C7RA01450C
(2017)Doi:10.1021/ml4002437
(2013)Doi:10.2514/2.3831
(1953)Doi:10.1016/j.jallcom.2013.07.012
(2013)Doi:10.1081/SCC-120018691
(2003)
