Homochiral NADH models in the pyrrolo[2,3-b]pyridine series bearing one or two chiral auxiliaries. Asymmetric reduction of methyl benzoylformate and N-acetyl-enamines. Influence of the magnesium salt concentration on the asymmetric induction of reductions

Article abstract of DOI:10.1016/S0957-4166(97)00436-9

The synthesis of NADH models in the pyrrolo[2,3-b]pyridine series bearing one or two chiral auxiliaries either at the pyridine or at the pyrrole ring is described. These models were involved in the reduction of methyl benzoylformate. The reactivity of the