Enantioselective synthesis of (-)-indolizidine 167B

DOI: 10.1016/S0040-4039(99)00059-3

Source and publish data:

Tetrahedron Letters p. 1661 - 1664 (1999)

Update date:2022-08-10

Topics:

Authors:

Chalard, Pierre

Remuson, Roland

Gelas-Mialhe, Yvonne

Gramain, Jean-Claude

Canet, Isabelle

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Article abstract of DOI:10.1016/S0040-4039(99)00059-3

The enantioselective total synthesis of (-)-indolizidine 167B is described. The key step is the intramolecular cyclization of the chiral N- acyliminium ion 6. Indolizidine 167B was obtained in 7 steps and 17% yield from ethyl (R)-3-aminohexanoate, with an

Full text of DOI:10.1016/S0040-4039(99)00059-3

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Product name:Hexanoic acid, 3-[[(1R)-1-phenylethyl](phenylmethyl)amino]-, ethyl ester, (3R)-

Cas No:222425-48-1

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