Tetrahedron Letters p. 1661 - 1664 (1999)
Update date:2022-08-10
Topics:
Chalard, Pierre
Remuson, Roland
Gelas-Mialhe, Yvonne
Gramain, Jean-Claude
Canet, Isabelle
The enantioselective total synthesis of (-)-indolizidine 167B is described. The key step is the intramolecular cyclization of the chiral N- acyliminium ion 6. Indolizidine 167B was obtained in 7 steps and 17% yield from ethyl (R)-3-aminohexanoate, with an
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Doi:10.1039/c8nj04672g
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