Diverse modifications of the 4-methylphenyl moiety of TAK-779 by late-stage Suzuki-Miyaura cross-coupling

DOI: 10.1039/c3ob41873a

Source and publish data:

Organic and Biomolecular Chemistry p. 177 - 186 (2014)

Update date:2022-08-10

Topics:

Authors:

Junker, Anna

Schepmann, Dirk

Yamaguchi, Junichiro

Itami, Kenichiro

Faust, Andreas

Kopka, Klaus

Wagner, Stefan

Wuensch, Bernhard

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c3ob41873a

Chemokine receptor 5 (CCR5) antagonists provide a new therapeutic approach in the treatment of HIV-1 (AIDS). TAK-779 displays high affinity and selectivity for the CCR5 receptor and serves as a lead compound for the development of further antagonists. In

Full text of DOI:10.1039/c3ob41873a

Products guided by the article

Product name:5-(4-bromophenyl)pentanoic acid

Cas No:22647-95-6

R&D Labs maybe for 22647-95-6

LIAONING DMSO CHEMICALS CO.,LTD.

website:http://www.chinadmso.com

Contact:+86-427-6503033

Address:FLOOR 16, BLOCK A, FINANCIAL SQUARE, XINGLONGTAI DISTRICT, PANJIN CITY, LIAONING P.R. CHINA
Changzhou Screw International Trading Co., Ltd.

Contact:13906149256,18001495888

Address:Jiangsu，Jintanqu
Weihao Chemtech (ChangZhou) Co., Ltd.(expird)

Contact:051989185693

Address:NO 217 huangshan Rd ,Changzhou
Dongguan Albiya Energy Science and Technology Co.,Ltd

Contact:+86-769-22181286

Address:Huanan Industial Park, Dongguan,China
Tianjin Derchemist Sci-Tech Co., Ltd.

website:http://www.derchemist.com

Contact:+86-22-58627059

Address:Xinmao Science and Technology Park，Huayuan Industrial Park

Relevant to this article

Doi:10.1021/ja01477a007
(1961)
Photosensitized conversion of tryptophan to beta-carboline derivatives.

Doi:10.1111/j.1751-1097.1969.tb05923.x
(1969)
Formation of a promazine radical and promazine 5-oxide in the reaction of promazine with hydrogen peroxide: Mechanistic insight from kinetic and epr measurements

Doi:10.1002/kin.20454
(2010)
Determination of adsorption and kinetic parameters for methyl tert-butyl ether synthesis from tert-butyl alcohol and methanol

Doi:10.1006/jcat.2001.3180
(2001)
Coordination diversity in transition metal complexes with 4-aminoantipyrine tethered bis(imino)pyridine ligand: structures, superoxide dismutase and anticancer properties

Doi:10.1080/00958972.2020.1853109
(2020)
Doi:10.1016/S0040-4020(01)99443-8
(1966)

Article Doi