Synthesis and monitoring hormone activity of 3-epi-2-deoxy-20-hydroxyecdysone and analogues

Article abstract of DOI:10.1016/S0040-4020(97)00025-2

The minor ecdysteroid 3-epi-2-deoxy-20-hydroxyecdysone (3-epi-2-D-20-ECD) has been partially synthesized from 20-hydroxyecdysone. 2-D-5α-20-ECD and the 3-dehydro analogues, 3-dehydro-2-D-20-ECD and 3-dehydro-2-D-5α-20-ECD, have also been synthesized. Moulting hormone activity of these compounds has been studied using the Musca bioassay.