Synthesis of (+)-(R)-1-Amino-2,2-difluorocyclopropane-1-carboxylic acid through lipase-catalyzed asymmetric acetylation

DOI: 10.1246/cl.1999.405

Source and publish data:

Chemistry Letters p. 405 - 406 (1999)

Update date:2022-07-30

Topics:

Authors:

Kirihara, Masayuki

Takuwa, Tomofumi

Kawasaki, Masashi

Kakuda, Hiroko

Hirokami, Shun-Ichi

Takahata, Hiroki

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Article abstract of DOI:10.1246/cl.1999.405

(+)-(R)-1-Amino-2,2-difluorocyclopropane-1-carboxylic acid was synthesized via the lipase-catalyzed asymmetric acetylation of a pro-chiral diol as the key step.

Full text of DOI:10.1246/cl.1999.405

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