Chemical Communications p. 165 - 166 (1996)
Update date:2022-08-10
Topics:
Chen, Shui-Tein
Tsai, Chin-Far
Wang, Kung-Tsung
In the presence of an oxime in the reaction solution, papain and lipase P (Pseudomonas from Amano) catalysed the stereoselective transesterification of an N-protected amino acid or peptide ester to form an active (oxime) ester which in turn underwent peptide bond formation with several natural and unnatural amino acid derivatives (proline, N-methylglycine, N-methylalanine, α-methylphenylalanine).
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