α-Cyano-N-(2,5-dibromophenyl)-β-hydroxybut-2-enamide

DOI: 10.1107/S0108270199005727

Source and publish data:

Acta Crystallographica, Section C: Crystal Structure Communications p. 1364 - 1365 (1999)

Update date:2022-08-11

Topics:

Authors:

Ghosh, Sutapa

Uckun, Fatih M.

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Article abstract of DOI:10.1107/S0108270199005727

The title compound, C₁₁H₈Br₂N₂O₂ (LFM-A13), is the first reported BTK-specific tyrosine kinase inhibitor and the first antileukemic agent targeting BTK (Bruton's tyrosine kinase). The crystal structur

Full text of DOI:10.1107/S0108270199005727

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