Tetrahedron p. 15899 - 15914 (1998)
Update date:2022-08-11
Topics:
Chung, Sung-Kee
Ryoo, Chung Hwan
Yang, Hong Woon
Shim, Jeung-Yeop
Kang, Myung Goo
Lee, Ki Wha
King, Heui Il
A series of lanosterol and cholesterol derivatives with modified side chain structures, which might interfere with sterol C24-methyltransferase in the ergosterol biosynthesis as substrate analogs, have been synthesized. The in vitro bioassay studies have shown that some of these compounds, in particular with C24-amino- and thio-functionalities, possess potent antifungal activities. in vivo. Bioassays have also been carried out for the leading compounds.
View MoreAnhui Asahikasei Chemical Co., Ltd
Contact:86-551-4259770
Address:No. 88 Linquan Road Hefei Anhui China
Contact:+(852) 301-98033
Address:Flat C, 23/F, Lucky Plaza, 315-321 Lockhart Road, Wan Chai, Hong Kong
website:http://www.np-chem.com
Contact:0086-25-52346877
Address:199, Jian Ye Road, Nanjing, China
Henan PURUI Pharmaceutical Co., Ltd.
website:http://www.puruipharm.com
Contact:17739583555
Address:Yezhuangqiao,Xihua town, Henan province
ChangZhou XiaQing Chemical Co., Ltd.
Contact:+86-519-88721665
Address:3# Hengluo Road, Henglin Town, Changzhou City, Jiangsu Province,China
Doi:10.1016/S0022-1139(03)00087-3
(2003)Doi:10.1021/ja01609a015
(1955)Doi:10.1002/hlca.19880710208
(1988)Doi:10.1016/j.ica.2017.12.011
(2018)Doi:10.3906/kim-1710-13
(2018)Doi:10.1039/c0cc01806f
(2010)