Chemistry of Natural Compounds p. 83 - 87 (1985)
Update date:2022-08-11
Topics:
Nakova, E. P.
Tolkachev, O. N.
The synthesis of stebisimine, (+/-)-obaberine, and (+/-)-isotetrandrine has been effected by the cyclocondensation of 5-acetyl-2-methoxyphenyl 4'-acetylphenyl ether with 5-(β-aminoethyl)-2,3-dimethoxyphenyl 4'-(β-aminoethyl)-2'-methoxyphenyl ether and sulfur through the stage of obtaining the corresponding biscyclophenylthioacetamides which were converted into the desired compounds by Bischler-Napieralski cyclization and reduction of the corresponding bismethiodides.
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