Synthetic Communications p. 3007 - 3013 (1995)
Update date:2022-08-12
Topics:
Barbry
Pasquier
Faven
Alkylation of phenylacetonitriles is performed by solid-liquid phase transfer catalysis in 1-3 minutes under microwave irradiation (one hour with a two-phase system). These nitriles can be quickly hydrolysed in a microwave oven to yield the corresponding amides or acids according to the reaction time.
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