Tetrahedron Letters p. 3243 - 3246 (1980)
Update date:2022-08-11
Topics:
Matteucci, M. D.
Caruthers, M. H.
Zinc bromide has been observed to detritylate specifically 5'-trityldeoxy-deoxynucleosides whereas 3'-trityl ethers are not cleaved.Of additional practical consideration and in contrast to protic acids, no depurination was observed with this reagent.
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