Incorporation of 2-C-methyl-D-erythritol, a putative isoprenoid precursor in the mevalonate-independent pathway, into ubiquinone and menaquinone of Escherichia coli

DOI: 10.1016/S0040-4039(97)01392-0

Source and publish data:

Tetrahedron Letters p. 6181 - 6184 (1997)

Update date:2022-08-11

Topics:

Authors:

Duvold, Tore

Cali, Patrizia

Bravo, Jean-Michel

Rohmer, Michel

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Article abstract of DOI:10.1016/S0040-4039(97)01392-0

Incorporation of deuterium labelled 2-C-methyl-D-erythritol into isoprenoid side-chains of ubiquinone and menaquinone from Escherichia coli strongly supports the proposed intermediate role of this branched sugar derivative in the mevalonate independent pathway for isoprenoid biosynthesis via glyceraldehyde 3-phosphate and pyruvate.

Full text of DOI:10.1016/S0040-4039(97)01392-0

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