Planta Medica p. 73 - 74 (1998)
Update date:2022-08-16
Topics:
Yang, Hyun Ok
Han, Byung Hoon
The water extract of Biota orientalis showed a potent inhibitory effect on platelet activating factor (PAF) binding to rabbit platelets using <3H>PAF as a ligand in our previous screeening studies for Korean medicinal antagonists by the activityguided purification studies.Another active compound, compound 1 (IC50=2.3*10-5 M, 7.48 +/- 2.11 μg/ml, n=4) was isolated from the title plant.The chemical structure of compound 1 was elucidated as pinusolidic acid by chemical and spectrometric analyses.
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