Syntheses and hypotensive properties of substituted 2-aminotetralins

DOI: 10.1002/jps.2600740110

Source and publish data:

Journal of Pharmaceutical Sciences p. 37 - 39 (1985)

Update date:2022-08-17

Topics:

Authors:

Repke Repke

Clark Clark

Kluge Kluge

Muchowski

Strosberg

Lee Lee

Whiting Whiting

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Article abstract of DOI:10.1002/jps.2600740110

The synthesis and activity in the spontaneously hypertensive rat of several 4-(1,2,3,4-tetrahydronaphthyl-2-amino)-1-(4-fluorophenyl)-1-butanones is reported. Maximal antihypertensive activity was associated with 5,6-dimethoxy substitution in the aminotetralin moiety.

Full text of DOI:10.1002/jps.2600740110

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