Syntheses and hypotensive properties of substituted 2-aminotetralins

DOI: 10.1002/jps.2600740110

Source and publish data:

Journal of Pharmaceutical Sciences p. 37 - 39 (1985)

Update date:2022-08-17

Topics:

Authors:

Repke Repke

Clark Clark

Kluge Kluge

Muchowski

Strosberg

Lee Lee

Whiting Whiting

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/jps.2600740110

The synthesis and activity in the spontaneously hypertensive rat of several 4-(1,2,3,4-tetrahydronaphthyl-2-amino)-1-(4-fluorophenyl)-1-butanones is reported. Maximal antihypertensive activity was associated with 5,6-dimethoxy substitution in the aminotetralin moiety.

Full text of DOI:10.1002/jps.2600740110

Products guided by the article

Product name:4-amino-1-(4-fluorophenyl)-1-butanone ethylene ketal

Cas No:3308-93-8

R&D Labs maybe for 3308-93-8

Wuhan Sunrise Pharmaceutical Technology Co., Ltd

Contact:+86-27-83314682

Address:Room 340, New material Industrial base No.17, Gu Tian Five Lu , Qiaokou District, Wuhan , China
SHANDONG QINGYUNCHANGXIN CHEMICAL SCIENCE-TECH CO.,LTD

Contact:86-21-60560171

Address:1689Donghuan Rade,Qingyun County, Dezhou City, Shandong,China
Zibo Kunran Enterprises Co. LTD

website:http://www.kunranchem.com

Contact:0086 533 5200669

Address:No. 96 Jinjing Avenue, Zibo, Shandong, China
H&Y International Group Ltd

Contact:+86-571-86491666

Address:SHI XIANG ROAD
Tianjin Crest Pharmaceutical R&D Co., Ltd. （Tianjin Yao Technology Development Co., Ltd.）(expird)

Contact:+86-22-66211386

Address:Building B5-405, No, 80 4th Avenue, TEDA, Tianjin, China P.R. 300457

Relevant to this article

Study on catalytic centres of activated carbons modified in oxidising or reducing conditions

Doi:10.1016/j.molcata.2014.09.014
(2014)
Metatitanic acid pseudomorphs after titanyl sulfates: Nanostructured sorbents and precursors for crystalline titania with desired particle size and shape

Doi:10.1021/acs.cgd.7b01349
(2017)
Synthesis of a biferrocene diphosphine ligand with only planar chirality and its application in the Rh-catalyzed asymmetric hydrogenation of β-keto sulfones

Doi:10.1016/j.tetasy.2007.01.009
(2007)
Doi:10.1002/hlca.19320150122
(1932)
Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of 2-phenyl- or hydroxylated 2-phenyl-4-aryl-5H-indeno[1,2-b]pyridines

Doi:10.1016/j.bmc.2015.04.031
(2015)
Mechanism of O-Atom Transfer from Nitrite: Nitric Oxide Release at Copper(II)

Doi:10.1021/acs.inorgchem.1c00625
(2021)

Article Doi