Journal of Pharmaceutical Sciences p. 37 - 39 (1985)
Update date:2022-08-17
Topics:
Repke
Clark
Kluge
Muchowski
Strosberg
Lee
Whiting
The synthesis and activity in the spontaneously hypertensive rat of several 4-(1,2,3,4-tetrahydronaphthyl-2-amino)-1-(4-fluorophenyl)-1-butanones is reported. Maximal antihypertensive activity was associated with 5,6-dimethoxy substitution in the aminotetralin moiety.
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