A simple route to methyl 5S-(benzoyloxy)-6-oxohexanoate, a key intermediate in leukotriene synthesis

DOI: 10.1016/S0040-4039(00)89063-2

Source and publish data:

Tetrahedron Letters p. 3355 - 3356 (1990)

Update date:2022-08-30

Topics:

Authors:

Hayes, Roy

Wallace, Timothy W.

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Article abstract of DOI:10.1016/S0040-4039(00)89063-2

Methyl 5S-(benzoyloxy)-6-oxohexanoate 2, an intermediate in synthetic routes to the lipoxygenase-derived arachidonic acid metabolite leukotriene B₄, is available in three steps from 2-cyclohexen-1-one, using Schreiber's unsymmetrical ozonolysis protocol.

Full text of DOI:10.1016/S0040-4039(00)89063-2

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Product name:3-Benzoyloxycyclohexene

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