Journal of the American Chemical Society p. 1746 - 1751 (2020)
Update date:2022-08-22
Topics:
Quan, Yangjian
Lan, Guangxu
Fan, Yingjie
Shi, Wenjie
You, Eric
Lin, Wenbin
We report the design of a new multifunctional metal-organic layer (MOL), Hf12-Ir-OTf, comprising triflate (OTf)-capped Hf12 secondary building units (SBUs) and photosensitizing Ir(DBB)[dF(CF3)ppy]2+ [DBB-Ir-F, DBB = 4,4′-di(4-benzoato)-2,2′-bipyridine; dF(CF3)ppy = 2-(2,4-difluorophenyl)-5-(trifluoromethyl)pyridine] bridging ligands. Hf12-Ir-OTf effectively catalyzed dehydrogenative cross-couplings of heteroarenes with ethers, amines, and unactivated alkanes with turnover numbers of 930, 790, and 950, respectively. Hf12-Ir-OTf also competently catalyzed late-stage functionalization of bioactive and drug molecules such as caffeine, Fasudil, and Metyrapone. The superior catalytic performance of Hf12-Ir-OTf over a mixture of photoredox catalyst and stoichiometric amounts of Br?nsted acids or substoichiometric amounts (20 mol %) of Lewis acids is attributed to the close proximity (1.2 nm) between photoredox and Lewis acid catalysts in Hf12-Ir-OTf, which not only facilitates the reaction between the carbon radical and the activated heteroarene but also accelerates the electron transfer from the nitrogen radical intermediate to the Ir(IV) species in the catalytic cycle.
View MoreShandong Loyal Chemical industrial Co.,Ltd
Contact:0533-7451788
Address:Linzi Chemical Industrial Park, Zibo, Shandong Province
Contact:86-379-63338609
Address:Jiudian Village,Deting Town,Song County,Luoyang
Contact:86-898-65311214
Address:Room 102, BLDG. 68 Jiangnan City, No. 66 Heping Road,Haikou, Hainan, China
Contact:+86 512 6287 2180
Address:398 Ruoshui Road, Suzhou Industrial Park, Suzhou, Jiangsu, P. R. China
Tianjin Dongchang Fine Chemical Industry Co., Ltd.
Contact:+86-22-29894595
Address:Economic Developing Zone, Ji County, Tianjin, China
Doi:10.1002/cssc.201601785
(2017)Doi:10.1021/ja00217a054
(1988)Doi:10.1039/ft9918702661
(1991)Doi:10.1007/s10562-014-1346-x
(2014)Doi:10.1021/jo9818982
(1998)Doi:10.1039/c3ra00133d
(2013)