Chemistry Letters p. 107 - 110 (1981)
Update date:2022-08-11
Topics:
Ishikawa, Nobuo
Takaoka, Akio
Dimethyl and diethyl fluoromalonates were prepared by the stepwise basic alcoholysis of hexafluoropropene in a total yield of 50 - 55 percent.These dialkyl fluoromalonates were alkylated with alkyl halides, and the resulting dialkyl α-fluoroalkylmalonates were cyclized with urea affording 5-fluorobarbituric acid derivatives.
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