Journal of Medicinal Chemistry p. 1457 - 1464 (1984)
Update date:2022-08-11
Topics:
Bailey, Denis M.
DeGrazia, C. George
Hoff, Stephanie J.
Schulenberg, Patsy L.
O'Connor, John R.
et al.
A series of N,N'-polyalkylenebis<4-(substituted-amino)pyridines> has been prepared, and members have been evaluated as potential anti-dental plaque agents.From among the most active members of the series, one compound, N,N'-<1,10-decanediyldi-1(4H)-pyridinyl-4-ylidene>bis(1-octanamine) dihydrochloride, octenidine, was selected as a candidate for clinical study.
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