Sterols in Marine Invertebrates. 49. Isolation and Structure Elucidation of Eight New Polyhydroxylated Sterols from the Soft Coral Sinularia dissecta

Article abstract of DOI:10.1021/jo00209a016

A new group of polyhydroxylated sterols - all of them possessing an 11α-hydroxy substituents of potential utility as corticosteroid intermediates - has been isolated from the soft coral Sinularia dissecta.Their general structure was deduced from spectral data (500-MHz and 360-MHz 1H and 13C NMR and MS) and their stereochemistry was determined by correlating the respective spectral data (1H and 13C NMR) with those of synthetic sterols with similar structure and known configuration.