In search of acyclic analogues as universal nucleosides in degenerate probes

Article abstract of DOI:10.1080/15257779508012532

Five acyclic nucleoside analogues with unnatural base moieties have been synthesized of which three successfully were incorporated into oligonucleotides. The acyclic analogue containing the base 5-nitroindazole was the least discriminating and should be further pursued for use as a universal nucleoside analogue.

Full text of DOI:10.1080/15257779508012532

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Nucleosides and Nucleotides
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In Search of Acyclic Analogues as
Universal Nucleosides in Degenerate
Probes
A. Van Aerschot a , C. Hendrix a , G. Schepers a , N. Pillet a & P.
Herdewijn a
a Laboratory of Medicinal Chemistry , Rega Institute for Medical
Research , Minderbroedersstraat, 10, B-3000, Leuven, Belgium
Published online: 16 Feb 2007.
To cite this article: A. Van Aerschot , C. Hendrix , G. Schepers , N. Pillet & P. Herdewijn (1995)
In Search of Acyclic Analogues as Universal Nucleosides in Degenerate Probes, Nucleosides and
Nucleotides, 14:3-5, 1053-1056
To link to this article: http://dx.doi.org/10.1080/15257779508012532
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