Convenient synthesis of novel macrocyclic urethanes: Alkoxycarbonylation of amines and ring-closing metathesis strategy

Article abstract of DOI:10.1016/S0040-4039(98)00153-1

Alkoxycarbonylation of amines followed by ring-closing metathesis of the resulting dienes with Grubbs catalyst (25-50 mol%) provided convenient access to 14-16 membered macrocyclic urethanes in very good yields.