Formal synthesis of Ambrox and 9-epiambrox

Article abstract of DOI:10.1080/00397919608003554

(-)-Drimenol (5) was used as starting material for the synthesis of diastereoisomeric diols 3 and 4, through the nitrile 7. Compounds 3 and 4 are the direct precursors of Ambrox (1) and 9-epiambrox (2).

Full text of DOI:10.1080/00397919608003554

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Formal Synthesis of Ambrox®
and 9-Epiambrox
M. Cortés a , V. Armstrong a , M. E. Reyes a , J. López
a & E. Madariaga a
a Facultad de Química. Pontificia Universidad
Católica de Chile, Casilla 306. Correo 22., Santiago,
Chile
Published online: 21 Aug 2006.
To cite this article: M. Cortés , V. Armstrong , M. E. Reyes , J. López & E. Madariaga
(1996): Formal Synthesis of Ambrox® and 9-Epiambrox, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 26:10,
1995-2002
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