Efficient mitomycin C coupling with stable p-nitrophenyl-benzyl carbonates using N-hydroxybenzotriazole as a catalytic additive

DOI: 10.1016/S0040-4039(97)01159-3

Source and publish data:

Tetrahedron Letters p. 5261 - 5264 (1997)

Update date:2022-08-11

Topics:

Authors:

Dubowchik, Gene M.

King, H. Dalton

Pham-Kaplita, Kahnie

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Article abstract of DOI:10.1016/S0040-4039(97)01159-3

Mitomycin C benzyl carbamates were prepared in high yield from stable p-nitrophenyl carbonates in the presence of catalytic amounts of 1-hydroxybenzotriazole/diisopropylethylamine in DMF.

Full text of DOI:10.1016/S0040-4039(97)01159-3

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