Enantioselective oxidation of diols by secondary alcohol dehydrogenase from Geotrichum sp. WF9101

Article abstract of DOI:10.1271/bbb.60.1191

Geotrichum sp. WF9101 could degrade (S)-(+)-1,2-propanediol, (S)-(+)- 1,3-butanediol, and (2S,4S)-(+)-2,4-pentanediol, but not the corresponding enantiomers. An NAD⁺-linked secondary alcohol dehydrogenase purified from the strain showed the same enantioselective oxidations towards these diols. This enzyme is proposed to be useful for the preparation of (R)-(-)-diols from the racemates of these diols.

Full text of DOI:10.1271/bbb.60.1191

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Enantioselective Oxidation of Diols by Secondary
Alcohol Dehydrogenase from Geotrichum sp. WF9101
a
a
a
ab
Moir Tatsuma , Sakimoto Michio , Kagi Takashi & Sakai Takuo
a
Osaka Agricultural and Forestry Research Center, Syakudo 442, Hahikino-shi, Osaka
83, Japan
5
b
Department of Applied Biological Chemistry, College of Agriculture, University of Osaka
Prefecture, 1-1 Gakuen-cho, Sakai-shi, Osaka 593, Japan
Published online: 12 Jun 2014.
To cite this article: Moir Tatsuma, Sakimoto Michio, Kagi Takashi & Sakai Takuo (1996) Enantioselective Oxidation of Diols
by Secondary Alcohol Dehydrogenase from Geotrichum sp. WF9101, Bioscience, Biotechnology, and Biochemistry, 60:7,
1191-1192, DOI: 10.1271/bbb.60.1191
To link to this article: http://dx.doi.org/10.1271/bbb.60.1191
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