Synthesis and physicochemical studies of partially phosphate-methylated oligodeoxyribonucleotides

DOI: 10.1016/S0040-4039(00)73809-3

Source and publish data:

Tetrahedron Letters p. 5899 - 5902 (1993)

Update date:2022-08-11

Topics:

Authors:

Vinogradov

Asseline

Thuong Thuong

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Article abstract of DOI:10.1016/S0040-4039(00)73809-3

Partially phosphate-methylated oligodeoxyribonucleotides have been synthesized on an oxalyl-CPG derivatized support using an isopropoxyacetyl group for the protection of the exocyclic amine of the nucleic bases. Hybridization properties with the target sequence have been studied by absorption spectroscopy.

Full text of DOI:10.1016/S0040-4039(00)73809-3

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