Nucleosides and Nucleotides p. 1657 - 1658 (1999)
Update date:2022-08-15
Topics:
Lengeler
Weisz
Molecular modeling was used to design novel nucleobases for the specific recognition of Watson-Crick base pairs within a triple helix. The synthesis for one of the nucleoside analogs is described in detail. Preliminary NMR measurements on the monomeric nucleobases in apolar solvents indicate preferred association modes and affinities towards a guanosine-cytidine Watson-Crick base pair.
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Doi:10.1021/je300339q
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(1913)Doi:10.1021/jp9831278
(1999)Doi:10.1055/s-1992-26190
(1992)