Targeted delivery of siRNA to hepatocytes and hepatic stellate cells by bioconjugation

DOI: 10.1021/bc100346n

Source and publish data:

Bioconjugate Chemistry p. 2119 - 2127 (2010)

Update date:2022-08-10

Topics:

Authors:

Zhu, Lin

Mahato, Ram I.

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Article abstract of DOI:10.1021/bc100346n

Previously, we successfully conjugated galactosylated poly(ethylene glycol) (Gal-PEG) to oligonucleotides (ODNs) via an acid labile ester linker (Zhu et al., Bioconjugate Chem. 2008, 19, 290-8). In this study, sense strands of siRNA were conjugated to Gal

Full text of DOI:10.1021/bc100346n

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