Carbamoyl and thiocarbamoyl lithium: A new route by naphthalene-catalysed chlorine-lithium exchange

Article abstract of DOI:10.1016/S0040-4039(00)61613-1

The reaction of N,N-diisopropylcarbamoyl or N,N-dimethylthiocarbamoyl chloride (1a or 1b) with an excess of lithium powder and a catalytic amount of naphthalene (3 mol %) in the presence of a carbonyl compound 2 at temperatures ranging between -78 and 20°