Antiviral activities of β-enantiomers of 3′-substituted-3′-deoxythymidine analogs

Article abstract of DOI:10.1080/07328319708006172

Several β-L-3′-substituted-3′-deoxythymidine were stereospecifically synthesized. None of these analogs inhibited HIV-1 nor HBV replication in vitro suggesting that these β-L-pyrimidine derivatives may not be efficiently phosphorylated inside the cells Copyright

Full text of DOI:10.1080/07328319708006172

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Nucleosides and Nucleotides
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Antiviral Activities of β-Enantiomers
of 3′-Substituted-3′-deoxythymidine
Analogs
b
a
a
Abdesslem Faraj , M. Abdelaziz El Alaoui , Geraldine Pavia
,
b
b
c
Gilles Gosselin , Jean-Louis Imbach , Raymond F. Schinazi
&
a
Jean Pierre Sommadossi
a
University of Alabama at Birmingham , Birmingham, AL, USA
University of Montpellier II , 34095, Montpellier, France
VA Medical Center/Emory University , Decatur, GA, USA
b
c
Published online: 16 Aug 2006.
To cite this article: Abdesslem Faraj , M. Abdelaziz El Alaoui , Geraldine Pavia , Gilles Gosselin ,
Jean-Louis Imbach , Raymond F. Schinazi & Jean Pierre Sommadossi (1997) Antiviral Activities of
β-Enantiomers of 3′-Substituted-3′-deoxythymidine Analogs, Nucleosides and Nucleotides, 16:7-9,
287-1290, DOI: 10.1080/07328319708006172
1
To link to this article: http://dx.doi.org/10.1080/07328319708006172
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