New synthesis of leukotriene B3 methyl ester from bis(trimethylsilyl) unsaturated derivatives

DOI: 10.1016/S0040-4020(98)00146-X

Source and publish data:

Tetrahedron p. 4327 - 4336 (1998)

Update date:2022-08-11

Topics:

Authors:

Babudri, Francesco

Fiandanese, Vito

Hassan, Omar

Punzi, Angela

Naso, Francesco

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(98)00146-X

A new synthesis of leukotriene B₃ methyl ester is reported starting from bis(trimethylsilyl) unsaturated derivatives as building blocks for the triene moiety of the leukotriene. The two stereogenic centers have been generated by enantioselective chemical reduction of two acetylenic ketones with both R- or S-Alpine Borane. The three conjugated double bonds system of the leukotriene has been assembled by Miyaura-Suzuki cross-coupling reaction.

Full text of DOI:10.1016/S0040-4020(98)00146-X

Products guided by the article

Product name:undec-1-yn-3-ol

Cas No:53735-49-2

R&D Labs maybe for 53735-49-2

Wuhan Shangrisyn chemicals Technology Co.,Ltd(expird)

Contact:+86-027-84466317 __ +86-15387123698

Address:wuhan - china
Luoyang Aoda chemical Co.,Ltd.

Contact:+86-379-67518785 67516588

Address:MiaoWan industry district,YanShi City,Henan,China
Beijing Harmony Chemical Co., Ltd.

Contact:86-010-84956928

Address:Room 207, Jin feng he B building, No 8 Xin Jie Kou Wai Street, Xi Cheng District, Beijing,PRC. 10008
Binzhou Holly Pharmaceutical Co.,Ltd.

Contact:74517

Address:No.15 Dapu Road,Huangpu District Shanghai,P.R.China
Jiangyin Tenghua Import&Export Co.,Ltd.

Contact:+86-510-86263875

Address:Room 402-B,9 Yanling Road, Jiangyin,Jiangsu, China

Relevant to this article

Synthesis of (¹⁴C₆-3,4,7,8,11,12)-(1E,5E,9E)- cyclododeca-1,5,9-triene

Doi:10.1002/jlcr.1265
(2007)
New Cu(II), Co(II) and Ni(II) azo-Schiff base complexes: Synthesis, characterization, catalytic oxidation of alkenes and DFT study

Doi:10.1016/j.poly.2021.115148
(2021)
C-H and C-F Bond Activations at a Rhodium(I) Boryl Complex: Reaction Steps for the Catalytic Borylation of Fluorinated Aromatics

Doi:10.1021/om500952x
(2015)
New alkoxycarbonyl complexes of palladium (II) and their role in carbonylation reactions carried out in the presence of an alkanol

Doi:10.1016/0304-5102(93)85049-Y
(1993)
Catalysis in peptide synthesis with active esters. I. Bifunctional catalysis in the aminolysis of benzyloxycarbonyl-L-phenylalanine p-nitrophenyl ester in dioxane.

Doi:10.1246/bcsj.42.1071
(1969)
Synthesis of Adamantanoid Ketones from Bridgehead Alcohols by the Hypoiodite Thermolysis-Cyclization Sequence

Doi:10.1021/jo01312a015
(1980)

Article Doi