Electrochemical investigation of some potential antibacterials, II

Article abstract of DOI:10.1139/v97-067

The electrochemical behaviour of 2-(4'-sulphonamoyl)hydrazonobutyrate- 1,3-diones and sulphonamoylazoaminobenzenes has been studied over a wide range of pH at dropping mercury as well as glassy carbon electrodes. Both types of compounds exhibited a 4c^- reduction reaction at both electrodes. At pH > 4.5; 2-(4'-sulphonamoyl)hydrazonobutyrate-1,3-diones exhibited a 2e^- reduction wave at higher potentials. Both compounds undergo a 2e^- oxidation reaction. On the basis of polarography, linear and cyclic voltammetry, controlled potential electrolysis, coulometry, and spectral analysis, a detailed mechanism has been postulated for the reduction as well as the oxidation. The electrochemical behaviour of 2-(4′-sulphonamoyl)hydrazonobutyrate-1,3-diones and sulphonamoylazoaminobenzenes has been studied over a wide range of pH at dropping mercury as well as glassy carbon electrodes. Both types of compounds exhibited a 4e^- reduction reaction at both electrodes. At pH>4.5, 2-(4′-sulphonamoyl)hydrazonobutyrate-1,3-diones exhibited a 2e^- reduction wave at higher potentials. Both compounds undergo a 2e^- oxidation reaction. On the basis of polarography, linear and cyclic voltammetry, controlled potential electrolysis, coulometry, and spectral analysis, a detailed mechanism has been postulated for the reduction as well as the oxidation.