Anti-AIDS agents-XXVI. Structure-activity correlations of gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues

DOI: 10.1016/S0968-0896(97)00118-1

Source and publish data:

Bioorganic and Medicinal Chemistry p. 1715 - 1723 (1997)

Update date:2022-08-10

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Authors:

Chen, Dao-Feng

Zhang, Shun-Xiang

Xie, Lan

Xie, Jing-Xi

Chen, Ke

Kashiwada, Yoshiki

Zhou, Bing-Nan

Wang, Pei

Cosentino, L. Mark

Lee, Kuo-Hsiung

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Article abstract of DOI:10.1016/S0968-0896(97)00118-1

Bioactivity-directed fractionation of an ethanolic extract of the stems of Kadsura interior led to the isolation and identification of 12 known lignans (1-12). Seven of these compounds (1, 6, 8-12) were active as anti-HIV agents. Gomisin-G (11) exhibited

Full text of DOI:10.1016/S0968-0896(97)00118-1

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