Gliclazide hydroxylation by rat liver microsomes

DOI: 10.3109/00498259509061922

Source and publish data:

Xenobiotica p. 1345 - 1354 (1995)

Update date:2022-08-16

Topics:

Authors:

Rieutord

Stupans Stupans

Shenfield

Gross Gross

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Article abstract of DOI:10.3109/00498259509061922

The metabolism of gliclazide to hydroxygliclazide has been investigated in Sprague-Dawley rat liver microsomes. The kinetics of hydroxygliclazide formation are consistent with Michaelis-Menten kinetics (mean (± SD, n = 3) apparent K(m) and V(max) = 256 ±

Full text of DOI:10.3109/00498259509061922

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