An improved synthesis of methyl (E)-5-nitro-2-pentenoate

Article abstract of DOI:10.1080/00397919208055414

A two-step synthesis of methyl (E)-5-nitro-2-pentenoate involving addition of nitrous acid to acrolein followed by Wittig olefination is described. The preparation can be routinely carried out on a 0.1 mole scale to afford the title compound in 45-50% overall yield as a 92:8 mixture of the E:Z double bond isomers.

Full text of DOI:10.1080/00397919208055414

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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An improved Synthesis
of Methyl (E)-5-Nitro-2-
Pentenoate
Richard A. Bunce a & J. Travis Parker a
a Department of Chemistry , Oklahoma State
University , Stillwater, OK, 74078—0447
Published online: 05 Dec 2006.
To cite this article: Richard A. Bunce & J. Travis Parker (1992) An improved Synthesis
of Methyl (E)-5-Nitro-2-Pentenoate, Synthetic Communications: An International
Journal for Rapid Communication of Synthetic Organic Chemistry, 22:3, 377-380, DOI:
10.1080/00397919208055414
To link to this article: http://dx.doi.org/10.1080/00397919208055414
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