Zirconium Catalyzed or Mediated Regioselective C-C Bond Formation Reactions of α,β-Unsaturated Acetals

Article abstract of DOI:10.1246/cl.1994.259

Zirconium-alkyne complexes or zirconacyclopentenes, which are easily prepared in situ from alkynes, reacted with acrolein diethylacetal to afford vinyl ether derivatives.The C-C bond formation proceeded exclusively at β-position of the α,β-unsaturated acetal.Zirconium catalyzed C-C bond formation reactions of α,β-unsaturated acetals with EtMgBr also proceeded at β-position exclusively.