The Directing Ability of the Methylthio Substituent in Lithiathion Reactions of Thiophenes

DOI: 10.1021/jo00207a019

Source and publish data:

Journal of Organic Chemistry p. 1002 - 1004 (1985)

Update date:2022-08-29

Topics:

Authors:

Taylor, Edward C.

Vogel, Dennis E.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00207a019

A method for regiospecific electrophilic substitution of 3-(methylthio)thiophene in either the 2- or 5-position has been developed on the basis of a combination of bromination, metal-halogen exchange, and controlled rearrangement of 2-bromo-5-lithio-3-(methylthio)thiophene to 5-bromo-2-lithio-3-(methylthio)thiophene.

Full text of DOI:10.1021/jo00207a019

Products guided by the article

Product name:2-Thiophenecarboxylic acid, 3-(methylthio)-

Cas No:60166-80-5

R&D Labs maybe for 60166-80-5

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Contact:+86-21-5161 3915

Address:Shanghai YangPu
Shanghai Yuantai Chemical Products Co., Ltd

Contact:021--66129803

Address:Chengyin Road,Shanghai,China
GBXF SILICONES CO.,LTD

website:http://www.gbxfsilicones.com/

Contact:86-25-68900673

Address:He Country Provincial Fine Chemical Industrial Park of Chaohu city,Anhui province,China
Changsha Yihai Chemical Technology Co.,ltd

website:http://www.cs-yihai.com/

Contact:0731- 85620465

Address:Room 23005, unit 2, the northern building of Xiangsong international building , NO.259 Shaoshan Road , Changsha , Hunan, China.(mainland)
Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

website:http://www.shydtec.com

Contact:86-21-57721279

Address:Science and Technology Park, Songjiang District, Shanghai, China

Relevant to this article

Thermal Stimuli-Triggered Drug Release from a Biocompatible Porous Metal–Organic Framework

Doi:10.1002/chem.201701904
(2017)
Synthesis of Naphthoninhydrin

Doi:10.1021/jo00021a055
(1991)
Palladium catalyzed one-pot synthesis of 2-(pyridin-4-yl) quinolines via a multicomponent unprecedented reaction of pyridine-4-carbaldehyde, 2-iodoaniline and triethylamine

Doi:10.1039/c4ra08624d
(2014)
Adsorption and Microcalorimetric Measurements on the Interaction of CO and H₂ with Polycrystalline Ru and Ru/TiO₂ Catalyst

Doi:10.1006/jcat.1997.1717
(1997)
Synthesis and cytotoxicity evaluation of aryl triazolic derivatives and their hydroxymethine homologues against B16 melanoma cell line

Doi:10.1016/j.ejmech.2016.06.057
(2016)
Temperature for curing phthalonitrile-terminated poly(phthalazinone ether nitrile) reduced by a mixed curing agent and its curing behavior

Doi:10.1039/c5ra17234a
(2015)

Article Doi