A simple convenient method for the resolution of racemic 2,2'-dihydroxy-1,1'-binaphthyl using (S)-proline

Article abstract of DOI:10.1016/0957-4166(95)00008-D

The racemic mixture of 2,2'-dihydroxy-1,1'-binaphthyl has been resolved to obtain the R(+) and S(-) enantiomers in essentially pure forms by refluxing with (S)-proline (1eq.) in benzene in three successive operations.