Frankfurt shift, II: Further contributions on the intramolecular shift of N-oxides of tertiary cycloalkylamines to lactams (Frankfurt shift)

DOI: 10.1002/ardp.19943270307

Source and publish data:

Archiv der Pharmazie p. 163 - 167 (1994)

Update date:2022-08-30

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Authors:

Oelschlager

Schmidt Schmidt

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Article abstract of DOI:10.1002/ardp.19943270307

The basis knowledge of the Frankfurt shift could be extended by experiments on the kinetic isotopic effect, an experiment with incubation in ¹⁸O₂-atmosphere and a shift with 1-(4-fluorobenzyl)-piperidine-N-oxide (4). Furthermore the shift was established in a whole animal experiment (rat).

Full text of DOI:10.1002/ardp.19943270307

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