Tetrahedron Letters p. 4701 - 4704 (1993)
Update date:2022-08-30
Topics:
Molina, Pedro
Almendros, Pedro
Fresneda, Pilar M.
A new eight-step synthesis of the genotoxic amine Trp-P-2 in an overall yield of 14.4 percent is described.The key step, formation of γ-carboline ring, involves a tandem aza Wittig/electrocyclic ring closure process.
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