Chemical and Pharmaceutical Bulletin p. 1046 - 1051 (1997)
Update date:2022-08-10
Topics:
Kanazawa, Tsutomu
Ohkawa, Yuki
Kuda, Takashi
Minobe, Yasushi
Tani, Tadato
Nishizawa, Makoto
New γ-pyrones, 9'-oxopodopyrone (3) and 8-methyl-9'-oxopodopyrone (4) were isolated from the leaves of Gonystylus keithii, along with known γ- pyrones, 10'-oxopodopyrone (1) and 8-methyl-10'-oxopodopyrone (2). These γ- pyrones markedly inhibited the bovine parathyroid hormone (PTH)-induced Ca release from neonatal mouse calvaria in vitro. It is the first time that γ- pyrones showed inhibitory effects on bone resorption, and these compounds may be seed compounds of new drugs for osteoporosis.
View More
Suzhou Zhonghelong Chemical Tech Co., Ltd【License cancellation】
Contact:+86 571-12345678
Address:Dunhuang Road, Suzhou Industrial Park, No.128 building 701 room Mansion
Shanghai WinTide BioTechnology Co.,Ltd
Contact:86-21-37100630
Address:No. 908 Yunhe Road, Fengxian district, Shanghai
Anyang Double Circle Auxiliary CO.,LTD
Contact:0086-134 6082 4403
Address:dongfeng road, anyang city, henan province,china
Shandong Jusage Technology Co.,Ltd.
Contact:86-13406130167
Address:No.20,North Ride No.9 Road, Guangrao Economic Development Zone, Shandong Province
website:http://www.angchenchem.com
Contact:+86-510-88302099 82327577
Address:Rm. 404/405, Floor 4th, No. 983 FengXiang Road, Wuxi, China
Doi:10.1071/CH9930731
(1993)Doi:10.1021/ja400755e
(2013)Doi:10.1016/j.tetlet.2013.09.096
(2013)Doi:10.1039/JR9650004483
()Doi:10.1021/ja039549z
(2004)Doi:10.1039/c4ra05059b
(2014)
