Synthesis of unsymmetrically substituted α-aminoalkylphosphonate esters

Article abstract of DOI:10.1080/00397919508011823

The title compounds were designed as haptens for production of monoclonal antibodies as potential catalysts for phosphoryl transfer reactions of phosphates and phosphonates. These haptens conform to the 'bait and switch' model.

Full text of DOI:10.1080/00397919508011823

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Synthetic Communications: An
International Journal for Rapid
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Organic Chemistry
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Synthesis of Unsymmetrically
Substituted α-
Aminoalkylphosphonate Esters
Robert M. Moriarty a b , Kaiming Liu a , Hui Zhuang b
, David Lenz c , Alan Brimfield c & Chizhong Xia b
a Steroids, Ltd., 2201 W. Campbell Park Dr., Chicago,
IL, 60612
b University of Illinois at Chicago, Department of
Chemistry, Chicago, IL, 60607
c USAMRICD, Aberdeen Proving Ground., MD, 21010
Published online: 16 Feb 2007.
To cite this article: Robert M. Moriarty , Kaiming Liu , Hui Zhuang , David Lenz ,
Alan Brimfield & Chizhong Xia (1995): Synthesis of Unsymmetrically Substituted α-
Aminoalkylphosphonate Esters, Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 25:18, 2763-2773
To link to this article: http://dx.doi.org/10.1080/00397919508011823
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