Carboxyamidation of purine nucleosides: New secondary 8- carboxamidopurine nucleosides

Article abstract of DOI:10.1080/07328319708001344

Palladium catalyzed carboxyamidation at the 8-position of 8- bromoadenosine and 8-bromoguanosine nucleosides is a versatile reaction, which allows primary, secondary, heterocyclic, aromatic amine and amino acids to be incorporated into purine nucleosides.

Full text of DOI:10.1080/07328319708001344

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Nucleosides and Nucleotides
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Carboxyamidation of Purine Nucleosides:
New Secondary 8-Carboxamidopurine
Nucleosides
Chi Tu a , Charlene Keane a & Bruce Eaton a
a Medicinal Chemistry Department , NeXstar Pharmaceuticals Inc. ,
2860 Wilderness Place, Boulder, CO, 80301
Published online: 22 Aug 2006.
To cite this article: Chi Tu , Charlene Keane & Bruce Eaton (1997) Carboxyamidation of Purine
Nucleosides: New Secondary 8-Carboxamidopurine Nucleosides, Nucleosides and Nucleotides, 16:3,
227-237, DOI: 10.1080/07328319708001344
To link to this article: http://dx.doi.org/10.1080/07328319708001344
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