A new approach to (+)-brefeldin A via a nickel-catalyzed coupling reaction of cyclopentenyl acetate and lithium 2-furylborate

Article abstract of DOI:10.1016/0040-4039(96)01291-9

Coupling reaction of 2 with 2-furylborate 14 in the presence of the nickel catalyst afforded 1,4-isomer 5 regio- and stereoselectively and the product 5 was applied to the synthesis of Bartlett's brefeldin intermediate 11.