Tetrahedron Letters p. 6973 - 6976 (1990)
Update date:2022-08-10
Topics:
Bajwa, Joginder S.
Anderson, Robert C.
An improved procedure for regiospecific O-alkylation of β-tetronic acids with primary and secondary alcohols, based upon Mitsunobu conditions, is presented.The reaction conditions are very mild and compatible with a variety of hydroxyl protecting groups such as MOM, t-BuMe2Si, isopropylidine and esters.
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