Bioorganic and Medicinal Chemistry Letters p. 1367 - 1370 (1996)
Update date:2022-08-11
Topics:
Bunker, Amy M.
Edmunds, Jeremy J.
Berryman, Kent A.
Walker, Donnelle M.
Flynn, Michael A.
Welch, Kathy M.
Doherty, Annette M.
Endothelin-1 is a potent vasoconstrictor which is thought to be involved in many human disease states. We have developed a series of indole non- peptide endothelin antagonists which display nanomolar receptor affinity. The representative compound from thi
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