Asymmetric synthesis of 4(R)tert-butyl-8a(S)hydroxycarbonyl-4,6,7,8,8a,9-hexahydro-1-alkylpyrr olo[3,2-f]indolizines via intramolecular iminium ion cyclization

Article abstract of DOI:10.1080/00397919708004802

Enantiomerically pure compounds embodying the 4,6,7,8,8a,9-hexahydropyrrolo[3,2-f]indolizine unit were synthesized via intramolecular iminium ion cyclization. An improved procedure for the preparation of the oxazolidinone 1 is also reported.

Full text of DOI:10.1080/00397919708004802

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Asymmetric
Synthesis of 4(R)Tert-
Butyl-8a(S)Hydroxycarbonyl-4,6,
Hexahydro-1-Alkyl-
Pyrrolo[3,2-f]Indolizines via
Intramolecular Iminium Ion
Cyclization
Rita Annunziata a , Marinella Ferrari a , Gianluca
Papeo a , Marina Resmini a & Massimo Sisti a
a Dipartimento di Chimica Organica e
Industriale , Università degli Studi di Milano ,
Via G. Venezian, 21, 20133, Milano, Italy
Published online: 19 Aug 2006.
To cite this article: Rita Annunziata , Marinella Ferrari , Gianluca Papeo ,
Marina Resmini & Massimo Sisti (1997) Asymmetric Synthesis of 4(R)Tert-
Butyl-8a(S)Hydroxycarbonyl-4,6,7,8,8a,9-Hexahydro-1-Alkyl-Pyrrolo[3,2-
f]Indolizines via Intramolecular Iminium Ion Cyclization, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 27:1, 23-38, DOI: 10.1080/00397919708004802
To link to this article: http://dx.doi.org/10.1080/00397919708004802
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