Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy (2020)
Update date:2022-08-16
Topics:
Li, Ming
Chao, Jianbin
Liu, Yaoming
Xu, Miao
Zhang, Yongbin
Huo, Fangjun
Wang, Juanjuan
Yin, Caixia
Hypochlorous acid, a type of reactive oxygen species, has been shown to play an important role in organisms. Nowadays, there are many kinds of fluorescence detecting mechanisms to detect hypochlorous acid in vivo. Due to the high selectivity, the mechanism of using the strong oxidation of hypochlorous acid to break carbon?carbon double bonds has been favored by many scientists. However, the reported probes of breaking carbon?carbon double bonds still had drawback such as slow response. Based on this, we introduced electron-withdrawing group malonitrile to accelerate the oxidation of hypochlorous acid, resulting in reaction time less than 150 s. Meanwhile, the probe exhibited excellent selectivity, optical stability, high sensitivity and the detection limit as low as 0.19 μM. More importantly, we also successfully proved the potential application of the probe for the detection of intracellular ClO? living cells and Arabidopsis root tip by fluorescence imaging.
View MoreShenZhen InnoSyn Biotech Co.,Ltd
website:http://www.innosyns.com
Contact:+86-755-28351685
Address:Floor 5 & 6, Building A1, HAIKEXING Strategic Innovative Industrial Park, 16 BaoShan Road, PingShan District
Taizhou YOJOY Chemical Co., Ltd.
Contact:13857143241
Address:Yangfu Industrial Park, Xianju, Zhejiang, P. R. China
Shanghai Rich Chemicals Co., Ltd
website:http://www.richchemical.com
Contact:+86-21-20255798
Address:Pudong Shanghai,China
WEIFANG RICHEM INTERNATIONAL LTD
Contact:86-536-2222176
Address:weifang,shandong
Changzhou LanXu Chemical Co.,ltd.(expird)
Contact:86-0519-86330911,13656129734,15261186386
Address:Room 524, Depart.Chemical, Changzhou Science and Eductaion town, Jiangsu, China;Factory: Haian Fine Chemical Industry Park,Nantong,Jiangsu,China
Doi:10.1002/hlca.19710540314
(1971)Doi:10.1002/anie.201702225
(2017)Doi:10.1002/ardp.19733061208
(1973)Doi:10.1055/s-2008-1072515
(2008)Doi:10.1021/ja01073a011
(1964)Doi:10.1007/BF00630187
(1992)