Efforts toward the total synthesis of (±)-toxicodenane A utilizing an oxidopyrylium-based [5+2] cycloaddition of a silicon-tethered BOC-pyranone

Article abstract of DOI:10.1016/j.tetlet.2020.152324

Synthetic efforts toward the tricyclic core of (±)-toxicodenane A are reported. This strategy takes advantage of the Feist-Benary furan annulation, Achmatowicz oxidative rearrangement, and oxidopyrylium-based [5+2] cycloaddition to access a key tetracycli